This volume presents a comprehensive collection of methods that have been instrumental to the current understanding of bacterial persisters. Chapters in the book cover topics ranging from general methods for measuring persister levels in
Escherichia coli
cultures, prools for the determination of the persister subpopulation in
Candida albicans
, quantitative measurements of Type I and Type II persisters using ScanLag, to
in vitro
and
in vivo
models for the study of the intracellular activity of antibiotics. Written in the highly successful
Methods in Molecular Biology
series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory prools, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge,
Bacterial Persistence: Methods and Prools
brings together the most respected researchers in bacterial persistence whose studies will remain vital to understanding this field for many years to come.